Work Packages

H2O has established an ambitious work plan to create an unprecedented, standardised data governance and infrastructure system across Europe to incorporate patients’ opinions and preferences in health care. The transformational nature of this project calls for intense collaboration in different spheres of expertise. Work has been organised around 4 general areas -governance, technical infrastructure, Observatories management and scientific coordination and project management- and 3 disease specific work groups focusing on diabetes, IBD and cancer.

Leading experts representing top-level organisations involved in H2O are working hand in hand across these different areas to deliver the expected results by 2025.  Next, you will find more detailed information about the scope of each work package.


Governance, Sustainability, Capabilities

This work package is responsible for defining the core concept of H2O. The scope of its work ranges involves devising the governance and legal framework, business architecture and quality assurance processes of the H2O ecosystem and ensuring the ability of the Observatories to collect new data and make them fit to be catalysts for interoperability with existing health data sources in the respective countries.



Technical infrastructure and interoperability

Work package 2 is focused on the design and implementation of the technical architecture of the H2O project, to support data management according to the project vision. These encompasses the implementation of a patient app for PRO data collection and a health care provider portal, and the development of a data integration platform, together with the overall Observatory framework.




This work package supports improvement in diabetes outcomes by collecting diabetes-related (Type 1 and Type 2) clinical and patient-reported health status data and by utilising these data to inform decision making by patients and health care providers. Amongst other objectives work package 3 is responsible for the development of a European consensus for a standardized, core data, and the preparation of multilingual guidance and education material for patients and health care professionals, besides providing data for segmentation of the population.



Inflammatory Bowel Disease

Work package 4 aims to contribute to address some of IBD significant unmet needs among different subpopulations and advance on greater patient-centricity and personalization of treatments to achieve better outcomes for IBD patients. This work package focuses on developing a European consensus for a minimum set of standardized outcomes for IBD, defining technological requirements and preparing multilingual guidance and education material for patients and health care professionals.



Cancer treatment

One of the main objectives of work package 5 consists of selecting appropriate standards for capturing the patient perspective of diseases through PRO instruments and wearables, in combination with clinical data to better capture the patient perspective of cancer and the impact of (novel) treatments. This work package also focuses on establishing technological requirements and designing strategies for patient participation, and physician awareness and engagement, in the collection and use of PROs.



Observatory management: communication and analysis

The main objective of work package 6 is to implement, operate and coordinate a network of H2O Observatories (including four National H2O and one Pan-European Umbrella H2O Observatory) and to ensure their sustainability and scalability in the long term. This work package is also responsible for conducting innovative data analysis, manage the gateway for users to anonymised and also to aggregated data, by overseeing and supporting the appropriate, governed and secure access to this data.



Scientific coordination & project management

Work package 7 is responsible for the project oversight and coordination at the strategic and scientific level through an effective management and communication structure. This work package provides project leadership and coordination through the application of the best scientific knowledge, vision, and collaborative work. It also focuses on the communication and dissemination strategy.